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Nonhuman Primate Models

II. Infection of Saimiri and Aotus Monkeys with Plasmodium vivax

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Malaria Methods and Protocols

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 72))

Abstract

Infections with human malaria parasites in New World monkeys offer opportunities to determine host-parasite interactions and relationships, to produce malarial antigens for diagnostic and molecular characterization, to conduct drug and vaccine efficacy trials, and to produce gametocytes for mosquito infectivity studies (1-7). Isolates of Plasmodium vivax from different geographic areas vary in their infectivity to monkeys and mosquitoes. Because they are human pathogens, standard precautions must be followed to avoid accidental infection. Additionally, primates require special housing and care as set forth in Guide for the Care and Use of Laboratory Animals. Protocols are approved by institutional Animal Care and Use Committees in accordance with U.S. Public Health Service Policy (1986).

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References

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Author information

Authors and Affiliations

  1. Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Chamblee, GA

    William E. Collins

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  1. William E. Collins
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Editor information

Editors and Affiliations

  1. Malaria Program, Naval Medical Research Center, Silver Spring, MD, USA

    Denise L. Doolan

  2. Department of Molecular Microbiology and Immunology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD, USA

    Denise L. Doolan

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© 2002 Humana Press Inc.

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Collins, W.E. (2002). Nonhuman Primate Models. In: Doolan, D.L. (eds) Malaria Methods and Protocols. Methods in Molecular Medicine™, vol 72. Humana Press. https://doi.org/10.1385/1-59259-271-6:85

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  • DOI: https://doi.org/10.1385/1-59259-271-6:85

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-823-3

  • Online ISBN: 978-1-59259-271-5

  • eBook Packages: Springer Protocols

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