Abstract
The glycosylphosphatidylinositol (GPI) anchors on mature proteins in the yeast Saccharomyces cerevisiae contain two different lipid moieties: diacylglycerols and ceramides (1,2). Most anchors contain a ceramide, but there are proteins, as for example, Gas1p, that only contain a diacylglycerol (2). The ceramide moiety is not present in the free GPI lipids, which are the precursors of the anchors, but it is introduced into the GPI anchors of GPI proteins by a remodeling mechanism (1,3,4).
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Reggiori, F., Canivenc-Gansel, E., Conzelmann, A. (1998). Analysis of the Lipid Moiety of GPI Anchor in the Yeast Saccharomyces cerevisiae . In: Gelb, M.H. (eds) Protein Lipidation Protocols. Methods in Molecular Biology, vol 116. Humana Press. https://doi.org/10.1385/1-59259-264-3:91
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DOI: https://doi.org/10.1385/1-59259-264-3:91
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