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Determination of Viral Infectivity

HSV, VZV, and CMV
  • David R. Harper
Part of the Methods in Molecular Medicine™ book series (MIMM, volume 24)

Abstract

Compared to the wide range of antibiotics that are available, the number of antiviral drugs is limited. However, herpesviruses have always been a major target for antiviral drug design, and there are a wide range of drugs at various stages of development. All of the assays described in this chapter provide relatively simple methods for plaque reduction assay of herpesviruses. Clearly, it is not possible to perform such assays on those herpesviruses that do not grow in adherent cells, such as Epstein-Barr virus. These require a different approach and are discussed elsewhere in this volume.

Keywords

Methylene Blue Maintenance Medium Sodium Hydrogen Carbonate Plaque Reduction Assay Overlay Medium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • David R. Harper
    • 1
  1. 1.Department of VirologySt. Bartholomew’s and the Royal London School of Medicine and DentistryLondonUK

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