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Hep AD38 Assay

A High-Throughput, Cell-Based Screen for the Evaluation of Compounds Against Hepatitis B Virus
  • Robert W. King
  • Stephanie K. Ladner
Part of the Methods in Molecular Medicine™ book series (MIMM, volume 24)

Abstract

Approximately 5% of the world’s population has been infected with hepatitis B virus (HBV). Ten percent of these adults will become chronic carriers, as will 95% of the infants infected perinatally. Those that do become chronically infected with HBV are at increased risk of developing liver dysfunction, cirrhosis, and liver failure (1). In addition, they also have a greater incidence of heptocellular carcinoma (2). Approximately two million chronic carriers die annually from liver disease attributed to infection by HBV (3).

Keywords

Saline Sodium Citrate Reporter Lysis Buffer Multichannel Pipeter Develop Liver Dysfunction Chroma Spin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • Robert W. King
    • 1
  • Stephanie K. Ladner
    • 1
  1. 1.The DuPont Merck Co.Wilmington

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