Hep AD38 Assay

A High-Throughput, Cell-Based Screen for the Evaluation of Compounds Against Hepatitis B Virus
  • Robert W. King
  • Stephanie K. Ladner
Part of the Methods in Molecular Medicine™ book series (MIMM, volume 24)


Approximately 5% of the world’s population has been infected with hepatitis B virus (HBV). Ten percent of these adults will become chronic carriers, as will 95% of the infants infected perinatally. Those that do become chronically infected with HBV are at increased risk of developing liver dysfunction, cirrhosis, and liver failure (1). In addition, they also have a greater incidence of heptocellular carcinoma (2). Approximately two million chronic carriers die annually from liver disease attributed to infection by HBV (3).


Saline Sodium Citrate Reporter Lysis Buffer Multichannel Pipeter Develop Liver Dysfunction Chroma Spin 
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Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • Robert W. King
    • 1
  • Stephanie K. Ladner
    • 1
  1. 1.The DuPont Merck Co.Wilmington

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