Abstract
The scanning transmission electron microscope (STEM) at Brookhaven National Laboratory* (BNL) is nearly unique in its ability not only to image isolated unstained and unshadowed biological molecules but also to obtain quantitative information about them such as their oligomeric state (1) (see Note 1). This makes it ideal, in principle, for looking at protein-DNA complexes and obtaining information about the masses bound. However, there are very stringent requirements on the purity and stability of the samples.
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References
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© 2001 Humana Press Inc., Totowa, NJ
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Wall, J.S., Simon, M.N. (2001). Scanning Transmission Electron Microscopy of DNA-Protein Complexes. In: Moss, T. (eds) DNA-Protein Interactions. Methods in Molecular Biology, vol 148. Humana Press. https://doi.org/10.1385/1-59259-208-2:589
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DOI: https://doi.org/10.1385/1-59259-208-2:589
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Print ISBN: 978-0-89603-625-3
Online ISBN: 978-1-59259-208-1
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