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In Vitro Mutagenesis Protocols pp 231–241Cite as

Random Mutagenesis for Protein Breeding

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Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 182))

Abstract

Mutagenesis is an essential process in evolution, generating an array of genetically unique organisms from which natural selection selects the best-suited to the immediate environment. Compatible and favorable mutations quickly converge; because offspring may inherit distinct advantageous mutations from both parents, and thus dramatically increase their survival rate. Parental crossing results in the accumulation of advantageous mutations in offspring. Evolutionary adaptation has allowed organisms to progressively specialize, and colonize, even in the most extreme of habitats.

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Author information

Authors and Affiliations

  1. Department of Biotechnology, Institute of Medical Biology, University of Trømso, Trømso, Norway

    Chris Fenton & Hao Xu

  2. Department of Biotechnology, Aalborg University, Aalborg, Denmark

    Evamaria I. Petersen & Steffen B. Petersen

  3. Department of Biotechnology, Institute of Medical Biology, University of Trømso, Trømso, Norway/ Aalborg University, Aalborg, Denmark

    M. Raafat El-Gewely

Authors
  1. Chris Fenton
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  2. Hao Xu
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  3. Evamaria I. Petersen
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  4. Steffen B. Petersen
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  5. M. Raafat El-Gewely
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Editor information

Editors and Affiliations

  1. Stratagene, La Jolla, CA

    Jeff Braman

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© 2002 Humana Press Inc.

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Fenton, C., Xu, H., Petersen, E.I., Petersen, S.B., El-Gewely, M.R. (2002). Random Mutagenesis for Protein Breeding. In: Braman, J. (eds) In Vitro Mutagenesis Protocols. Methods in Molecular Biology™, vol 182. Humana Press, Totowa, NJ. https://doi.org/10.1385/1-59259-194-9:231

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  • DOI: https://doi.org/10.1385/1-59259-194-9:231

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-0-89603-910-0

  • Online ISBN: 978-1-59259-194-7

  • eBook Packages: Springer Protocols

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