This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Cash, H. A., Woods, D. E., McCullough, B., Johanson, W. G., Jr., and Bass, J. A. (1979) A rat model of chronic respiratory infection with Pseudomonas aeruginosa. Am. Rev. Respir. Dis. 119, 453–459.
Davis, P. B., Drumm, M., and Konstan, M. W. (1996) Cystic fibrosis: State of the art. Am. J. Respir. Crit. Care Med. 154, 1229–1256.
Hancock, R. E. W., Mutharia, L. M., Chan, L., Darveau, R. P., Speert, D. P., and Pier, G. B. (1983) Pseudomonas aeruginosa isolates from patients with cystic fibrosis: A class of serum sensitive, nontypable strains deficient in lipopolysaccharide O side chains. Infect. Immunol. 42, 170–177.
Konstan, M. W. and Berger, M. (1993) Infection and inflammation in the lung in cystic fibrosis, in Cystic Fibrosis (Davis, P. B., ed.), MarcelDekker, New York, NY, pp. 219–276.
Konstan, M. W. and Berger, M. (1997) Current understanding of the inflammatory process in cystic fibrosis: Onset and etiology. Pediatr. Pulmonol. 24, 137–142.
Winnie, G. B., Klinger, J. D., Sherman, J. M., and Thomassen, M. J. (1982) Induction of phagocytic inhibitory activity in cats with chronic Pseudomonas aeruginosa pulmonary infection. Infect. Immun. 38, 1088–1093.
Pennington, J. E., Hickey, W. F., and Blackwood, L. L. (1981) Active immunization with lipopolysaccharide pseudomonas antigen for chronic pseudomonas bron-chopneumonia in guinea pigs. J. Clin. Invest. 68, 1140–1148.
Chung, A. T., Moss, R. B., Leong, A. B., and Novick, W. J., Jr. (1992) Chronic Pseudomonas aeruginosa endobronchitis in rhesus monkeys: I. Effects of pentoxyfylline on neutrophil influx. J Med. Primatol. 21, 357–362.
Starke, J. R., Edwards, M. S., Langston, C., and Baker, C. J. (1987) A mouse model of chronic pulmonary infection with Pseudomonas aeruginosa and Pseudomonas cepacia. Pediatr. Res. 22, 698–702.
van Heeckeren, A., Walenga, R., Konstan, M. W., Bonfield, T., Davis, P. B., and Ferkol, T. (1997) Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa. J. Clin. Invest. 100, 2810–2815.
Woods, D. E., Sokol, P. A., Bryan, L. E., Storey, D. G., Mattingly, S. J., Vogel, H. J., and Ceri, H. (1991) In vivo regulation of virulence in Pseudomonas aeruginosa associated with genetic rearrangement. J. Infect. Dis. 163, 143–149.
Konstan, M. W., Vargo, K. M., and Davis, P. B. (1990) Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection: Implications for antiinflammatory therapy in cystic fibrosis. Am. Rev. Respir. Dis. 141, 186–192.
Konstan, M. W., Byard, P. J., Hoppel, C. L., and Davis, P. B. (1995) Effect of highdose ibuprofen in patients with cystic fibrosis. N. Engl. J. Med. 332, 848–854.
Chmiel, J. F., Konstan, M. W., Knesebeck, J. E., Hilliard, J. B., Bonfield, T. L., Dawson, D. V., and Berger, M. (1999) IL-10 attenuates excessive inflammation in chronic pseudomonas infection in mice. Am. J. Respir. Crit. Care Med. 160, 2040–2047.
Yu, H., Hanes, H., Chrisp, C. E., Boucher, J. C., and Dretic, V. (1998) Microbial pathogenesis in cystic fibrosis: Pulmonary clearance of mucoid Pseudomonas aeruginosa and inflammation in a mouse model of repeated respiratory challenge. Infect. Immun. 66, 280–288.
Morissette, C., Skamene, E., and Gervais, F. (1995) Endobronchial inflammation following Pseudomonas aeruginosa infection in resistant and susceptible strains of mice. Infect. Immun. 63, 1718–1724.
Sapru, K., Stotland, P. K., and Stevenson, M. M. (1999) Quantitative and qualitative differences in bronchoalveolar inflammatory cells in Pseudomonas aeruginosa-resis- tant and susceptible strains of mice. Clin. Exp. Immunol. 115, 103–109.
Tam, M., Snipes, G. J., and Stevenson, M. M. (1999) Characterization of chronic bronchopulmonary Pseudomonas aeruginosa infection in resistant and susceptible inbred mouse strains. Am. J. Respir. Cell Mol. Biol. 20, 710–719.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Humana Press Inc.
About this protocol
Cite this protocol
Chmiel, J.F., Konstan, M.W., Berger, M. (2002). Murine Models of CF Airway Infection and Inflammation. In: Skach, W.R. (eds) Cystic Fibrosis Methods and Protocols. Methods in Molecular Medicine™, vol 70. Humana Press. https://doi.org/10.1385/1-59259-187-6:495
Download citation
DOI: https://doi.org/10.1385/1-59259-187-6:495
Publisher Name: Humana Press
Print ISBN: 978-0-89603-897-4
Online ISBN: 978-1-59259-187-9
eBook Packages: Springer Protocols