Abstract
The use of human neonatal keratinocyte cultures has provided a valuable tool in understanding the cellular and molecular mechanisms in skin growth, maintenance, and disease (1,2). With the onset of transgenic studies in mice, a new level of understanding development and disease has become apparent. Recently, several transgenic mouse models for skin diseases, such as the suprabasal integrin-expressing mouse model for psoriasis (3), and the bullous pemphigoid and integrin knock-out mice for blistering disorders (4-4) have shed light on direct molecular mechanisms underlying the onset of these disorders.
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Hodivala-Dilke, K. (2002). Primary Mouse Keratinocyte Culture. In: Wise, C. (eds) Epithelial Cell Culture Protocols. Methods In Molecular Medicineā¢, vol 188. Humana Press. https://doi.org/10.1385/1-59259-185-X:139
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DOI: https://doi.org/10.1385/1-59259-185-X:139
Publisher Name: Humana Press
Print ISBN: 978-0-89603-893-6
Online ISBN: 978-1-59259-185-5
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