Abstract
Troponin C (TnC) is a founding member of the EF-hand family of Ca2+ binding proteins. It functions as the receptor for Ca2+on the thin filament of striated muscle. Association of Ca2+, with the regulatory Ca2+binding sites in TnC, induces muscle contraction. Subsequent release of Ca2+allows the muscle to relax. There are two forms of TnC; one is found in fast skeletal muscle (sTnC), whereas the other is found in cardiac and slow skeletal muscle (cTnC).
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© 2002 Humana Press Inc.
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Putkey, J.A., Liu, W. (2002). Isolation of Recombinant CardiacTroponin C. In: Vogel, H.J. (eds) Calcium-Binding Protein Protocols. Methods in Molecular Biology™, vol 172. Humana Press. https://doi.org/10.1385/1-59259-183-3:151
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DOI: https://doi.org/10.1385/1-59259-183-3:151
Publisher Name: Humana Press
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Online ISBN: 978-1-59259-183-1
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