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Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease

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Book cover Meningococcal Vaccines

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 66))

Abstract

Alternative strategies exist for prevention of group B Neisseria meningitidis (meningococcal) disease through vaccination (see Chapters 5, 8, 13, 14 in this volume). However, the most promising approach to date has been the use of outer-membrane vesicle (OMV) vaccines for induction of bactericidal antibodies against cell-surface outer-membrane proteins (OMPs).

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Author information

Authors and Affiliations

  1. Division of Bacterial Products, Center for Biologics Evaluation and Research, Rockville, MD

    Carl E. Frasch

  2. Laboratory of Vaccine Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands

    Loek van Alphen

  3. Department of Vaccinology, National Institute of Public Health, Oslo, Norway

    Johan Holst & Einar Rosenqvist

  4. Bacterial Vaccine R⇐p;D Program, SmithKline Beecham Biologicals, Rixensart, Belgium

    Jan T. Poolman

Authors
  1. Carl E. Frasch
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  2. Loek van Alphen
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  3. Johan Holst
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  4. Jan T. Poolman
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  5. Einar Rosenqvist
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Editor information

Editors and Affiliations

  1. BC Research Institute for Children’s and Women’s Health, Vancouver, BC, Canada

    Andrew J. Pollard MD, PhD

  2. Wellcome Trust Centre for the Epidemiology of Infectious Disease, Oxford, UK

    Martin C.J. Maiden PhD

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© 2001 Humana Press Inc., Totowa, NJ

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Frasch, C.E., van Alphen, L., Holst, J., Poolman, J.T., Rosenqvist, E. (2001). Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease. In: Pollard, A.J., Maiden, M.C. (eds) Meningococcal Vaccines. Methods in Molecular Medicine™, vol 66. Humana Press. https://doi.org/10.1385/1-59259-148-5:81

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  • DOI: https://doi.org/10.1385/1-59259-148-5:81

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-801-1

  • Online ISBN: 978-1-59259-148-0

  • eBook Packages: Springer Protocols

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