Abstract
Interleukins are soluble peptide molecules that mediate the interaction between immunocompetent and haematopoietic cells and between the immune and neuroendocrine systems (1). They are produced by a variety of activated cells and exert their biological activities by binding to specific receptors on target cells. Interleukin-1β is the archetypal pleiotropic cytokine being produced by many cells and exerting its biological effects on almost all cell types (2). Interleukin-1β is a very potent proinflammatory cytokine and is involved in the host’s response to many antigenic challenges.
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El-Omar, E.M. (2001). 35Analysis of Single Nucleotide Polymorphisms in the Interleukin-1B Gene Using 5′ Nuclease Assays. In: O’Neill, L.A.J., Bowie, A. (eds) Interleukin Protocols. Methods in Molecular Medicine™, vol 60. Springer, Totowa, NJ. https://doi.org/10.1385/1-59259-146-9:409
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DOI: https://doi.org/10.1385/1-59259-146-9:409
Publisher Name: Springer, Totowa, NJ
Print ISBN: 978-0-89603-738-0
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