Abstract
Interleukin-2 (IL-2) was first discovered and characterized as T-cell growth factor (1). It is responsible for the growth of T cells and thus plays an important role in the proper functioning of the immune system. IL-2 has a high affinity receptor consisting of an α-, β-, and γ-chain. The γ- chain is shared with a number of other cytokines such as IL-3 and IL-7, which also play a role in cell growth (2). The IL-2 receptor β- chain also comprises part of the receptor for IL-15.
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Brennan, P., Athié-Morales, V. (2001). Analysis of Interleukin-2 Signaling Using Affinity Precipitations and Polyacrylamide Gel Electrophoresis. In: O’Neill, L.A.J., Bowie, A. (eds) Interleukin Protocols. Methods in Molecular Medicine™, vol 60. Springer, Totowa, NJ. https://doi.org/10.1385/1-59259-146-9:369
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DOI: https://doi.org/10.1385/1-59259-146-9:369
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