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Detection of DNA/Protein Interactions in Dopamine Receptor Genes

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Parkinson's Disease

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 62))

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In the previous chapter, we discussed practical methods to study transcription control mechanisms for the D1A dopamine receptor gene. Since these processes are mediated by a complex set of nuclear regulatory proteins that interact with specific DNA sequences, methods to delineate these interactions are paramount in understanding transcription control. In the case of the D1A gene, we found several consensus binding sites for known transcription factors on the 5’-noncoding region and examined their binding to the nuclear proteins and known transcription factors (1).

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References

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© 2001 Humana Press Inc.

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Lee, SH., Maral Mouradian, M. (2001). Detection of DNA/Protein Interactions in Dopamine Receptor Genes. In: Maral Mouradian, M. (eds) Parkinson's Disease. Methods in Molecular Medicine™, vol 62. Humana Press. https://doi.org/10.1385/1-59259-142-6:217

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  • DOI: https://doi.org/10.1385/1-59259-142-6:217

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-761-8

  • Online ISBN: 978-1-59259-142-8

  • eBook Packages: Springer Protocols

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