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Gene Therapy Protocols pp 187–202Cite as

Retrovirus-Mediated Gene Transfer to Human Hematopoietic Stem Cells

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Part of the book series: Methods in Molecular Medicine ((MIMM,volume 69))

Abstract

The ability of hematopoietic stem cells (HSCs) to engraft in a recipient and establish long-term repopulation of the hematopoietic system makes them ideal targets for gene therapy vectors designed to correct inherited or acquired diseases affecting the hematopoietic and immune systems.

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Author information

Authors and Affiliations

  1. Department of Molecular Genetics and Biochemistry, University of Pittsburgh, Pittsburgh, PA

    William P. Swaney

  2. Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA

    Enrico M. Novelli & John A. Barranger

  3. Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA

    Alfred B. Bahnson

Authors
  1. William P. Swaney
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  2. Enrico M. Novelli
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  3. Alfred B. Bahnson
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  4. John A. Barranger
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Editor information

Editors and Affiliations

  1. Brown University, Providence, RI

    Jeffrey R. Morgan

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© 2002 Humana Press Inc.

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Swaney, W.P., Novelli, E.M., Bahnson, A.B., Barranger, J.A. (2002). Retrovirus-Mediated Gene Transfer to Human Hematopoietic Stem Cells. In: Morgan, J.R. (eds) Gene Therapy Protocols. Methods in Molecular Medicine, vol 69. Springer, Totowa, NJ. https://doi.org/10.1385/1-59259-141-8:187

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  • DOI: https://doi.org/10.1385/1-59259-141-8:187

  • Publisher Name: Springer, Totowa, NJ

  • Print ISBN: 978-0-89603-723-6

  • Online ISBN: 978-1-59259-141-1

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