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The Purification of Mouse Hematopoietic Stem Cells at Sequential Stages of Maturation

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Hematopoietic Stem Cell Protocols

Part of the book series: Methods in Molecular Medicine ((MIMM,volume 63))

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Abstract

Hematopoietic stem cells (HSCs) are rare, self-renewing progenitors that give rise to all lineages of blood cells. HSCs can be found in all hematopoietic organs, from the para-aortic mesoderm (1),(2) and yolk sac (3),(4) in fetuses to the bone marrow (reviewed in ref. 5), blood and spleens of adults.

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Author information

Authors and Affiliations

  1. Departments of Internal Medicine and Cell and Developmental Biology, Howard Hughes Medical Institute and University of Michigan, Ann Arbor, MI

    Sean J. Morrison

Authors
  1. Sean J. Morrison
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Editor information

Editors and Affiliations

  1. University of Alabama-Birmingham, Birmingham, AL

    Christopher A. Klug PhD

  2. University of Kentucky, Lexington, KY

    Craig T. Jordan PhD

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© 2002 Humana Press Inc., Totowa, NJ

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Morrison, S.J. (2002). The Purification of Mouse Hematopoietic Stem Cells at Sequential Stages of Maturation. In: Klug, C.A., Jordan, C.T. (eds) Hematopoietic Stem Cell Protocols. Methods in Molecular Medicine, vol 63. Humana Press. https://doi.org/10.1385/1-59259-140-X:015

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  • DOI: https://doi.org/10.1385/1-59259-140-X:015

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-812-7

  • Online ISBN: 978-1-59259-140-4

  • eBook Packages: Springer Protocols

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