Membrane Invasion Culture System

  • Mary J. C. Hendrix
  • Elisabeth A. Seftor
  • Richard E. B. Seftor
Part of the Methods in Molecular Medicine™ book series (MIMM, volume 58)


Metastasis is the major cause of morbidity and death for cancer patients. A critical challenge to clinical and basic scientists is the development of improved prognostic methods to predict the metastatic aggressiveness of a patient’s individual tumor and especially to control local invasion-a key step in the metastatic cascade. Before effective therapeutic regimens can be planned, we must invest more effort in understanding the pathogenesis of tumor cell dissemination in order to identify better targets for clinical intervention.


Invasion Assay Polycarbonate Filter Filter Backing Invasion Data Matrix Barrier 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Humana Press Inc. 2001

Authors and Affiliations

  • Mary J. C. Hendrix
    • 1
  • Elisabeth A. Seftor
    • 2
  • Richard E. B. Seftor
  1. 1.Department of Anatomy and Cell Biology and The Holden Comprehensive Cancer Center, College of MedicineUniversity of IowaIowa City
  2. 2.Department of Anatomy and Cell Biology and The Holden Comprehensive Cancer Center, College of MedicineThe University of IowaIowa City

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