Abstract
SV40 large T antigen (T-ag) is an oncoprotein that induces transformation of cells through the binding and inactivation of the p53 tumor suppressor protein and the retinoblastoma family of proteins. This chapter focuses on the interaction of T-ag with the product of the retinoblastoma susceptibility gene (pRB), and two related proteins, p107 and p130 (1-3).
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© 2001 Humana Press Inc., Totowa, NJ
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Zalvide, J., DeCaprio, J.A., Stubdal, H. (2001). Binding of SV40 Large T Antigen to the Retinoblastoma Susceptibility Gene Product and Related Proteins. In: Raptis, L. (eds) SV40 Protocols. Methods in Molecular Biology™, vol 165. Humana Press. https://doi.org/10.1385/1-59259-117-5:213
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DOI: https://doi.org/10.1385/1-59259-117-5:213
Publisher Name: Humana Press
Print ISBN: 978-0-89603-653-6
Online ISBN: 978-1-59259-117-6
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