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Capillary Electrophoresis of Nucleic Acids pp 379–391Cite as

Ligand Binding to Oligonucleotides

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Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 163))

Abstract

We have been developing a method for the study of small-molecule interactions with DNA, typically with ligands of less than 1000 Dalton. Such interactions are of interest in biochemistry, where cell signaling may involve DNA at various stages, but the main driving force in our studies has been the potential for drug development, particularly in cancer, parasitic diseases, and inflammation.

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References

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Author information

Authors and Affiliations

  1. Department of Pharmaceutical Chemistry, University of Jordan, Amman, Jordan

    Imad I. Hamdan

  2. Department of Pharmaceutical Sciences, Strathclyde Institute for Biomedical Sciences, Glasgow, UK

    Graham G. Skellern & Roger D. Waigh

Authors
  1. Imad I. Hamdan
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  2. Graham G. Skellern
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  3. Roger D. Waigh
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Editor information

Editors and Affiliations

  1. Australian Genome Research Facility, University of Queensland, Brisbane

    Keith R. Mitchelson

  2. Walter & Eliza Hall Institute, Parkville, Australia

    Keith R. Mitchelson

  3. Biochip Research and Development Center State Key Laboratory for Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing, China

    Jing Cheng

  4. Aviva Biosciences Corporation, San Diego, CA

    Jing Cheng

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© 2001 Humana Press Inc.

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Hamdan, I.I., Skellern, G.G., Waigh, R.D. (2001). Ligand Binding to Oligonucleotides. In: Mitchelson, K.R., Cheng, J. (eds) Capillary Electrophoresis of Nucleic Acids. Methods in Molecular Biology™, vol 163. Humana Press. https://doi.org/10.1385/1-59259-116-7:379

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  • DOI: https://doi.org/10.1385/1-59259-116-7:379

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-765-6

  • Online ISBN: 978-1-59259-116-9

  • eBook Packages: Springer Protocols

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