Abstract
Glycamide surfactants are nonionic surfactants in which the hydrophilic moiety (an amino-alditol derivative) and the hydrophobic moiety (a fatty acid) are linked via an amide bond (1). Such sugar fatty amide surfactants can be obtained by chemical synthesis, using the Schotten-Baumann reaction between an amino-alditol and a fatty acid chloride in aqueous alkaline medium. An important drawback of this approach is the formation of salts by neutralization.
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Maugard, T., Remaud-Simeon, M., Monsan, P. (2001). Chemoselective Amidification of Amino-Polyols Catalyzed with Lipases in Organic Solvents. In: Vulfson, E.N., Halling, P.J., Holland, H.L. (eds) Enzymes in Nonaqueous Solvents. Methods in Biotechnology, vol 15. Humana Press. https://doi.org/10.1385/1-59259-112-4:325
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DOI: https://doi.org/10.1385/1-59259-112-4:325
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