Chemoselective Amidification of Amino-Polyols Catalyzed with Lipases in Organic Solvents

  • Thierry Maugard
  • Magali Remaud-Simeon
  • Pierre Monsan
Part of the Methods in Biotechnology book series (MIBT, volume 15)


Glycamide surfactants are nonionic surfactants in which the hydrophilic moiety (an amino-alditol derivative) and the hydrophobic moiety (a fatty acid) are linked via an amide bond (1). Such sugar fatty amide surfactants can be obtained by chemical synthesis, using the Schotten-Baumann reaction between an amino-alditol and a fatty acid chloride in aqueous alkaline medium. An important drawback of this approach is the formation of salts by neutralization.


Fatty Acid Methyl Ester Ester Synthesis Ethyl Lactate Differential Refractometer Candida Antarctica Lipase 
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Copyright information

© Humana Press Inc. 2001

Authors and Affiliations

  • Thierry Maugard
    • 1
  • Magali Remaud-Simeon
    • 1
  • Pierre Monsan
    • 1
  1. 1.Centre de Bioingenierie Gilbert Durand, Departément de Genie Biochimique et AlimentaireComplexe Scientifique de RangueilToulouse CedexFrance

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