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Microsatellite Instability Testing

  • Protocol
Colorectal Cancer

Part of the book series: Methods in Molecular Medicine ((MIMM,volume 50))

Abstract

Microsatellites are tandem repeats of simple sequences that occur abundantly and are randomly interspersed throughout the human genome. They typically consist of 10-50 copies of 1-6 bp motifs, and are characterized by a high degree of polymorphism. Despite the variability observed among individuals, microsatellite are replicated faithfully at each cell division in normal germline and somatic cells (1).

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© 2001 Humana Press Inc.

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Parc, Y.R., Halling, K.C. (2001). Microsatellite Instability Testing. In: M., S. (eds) Colorectal Cancer. Methods in Molecular Medicine, vol 50. Humana Press. https://doi.org/10.1385/1-59259-084-5:69

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  • DOI: https://doi.org/10.1385/1-59259-084-5:69

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-767-0

  • Online ISBN: 978-1-59259-084-1

  • eBook Packages: Springer Protocols

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