Abstract
Microsatellites are tandem repeats of simple sequences that occur abundantly and are randomly interspersed throughout the human genome. They typically consist of 10-50 copies of 1-6 bp motifs, and are characterized by a high degree of polymorphism. Despite the variability observed among individuals, microsatellite are replicated faithfully at each cell division in normal germline and somatic cells (1).
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Parc, Y.R., Halling, K.C. (2001). Microsatellite Instability Testing. In: M., S. (eds) Colorectal Cancer. Methods in Molecular Medicine, vol 50. Humana Press. https://doi.org/10.1385/1-59259-084-5:69
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DOI: https://doi.org/10.1385/1-59259-084-5:69
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