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The Use of a Continuous Culture System to Study the Antimicrobial Susceptibility of Bacteria in Biofilm

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Antibiotic Resistence

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 48))

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Abstract

The classical method for determining the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of an antibiotic is the tube test. Details of this test are well known and recognized methods are published (1). The recent development of the E-test (AB Biotest, Solna, Sweden), has been a significant development in the determination of MIC. This system is straightforward to perform and is suitable for larger scale work.

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Author information

Authors and Affiliations

  1. Coventry Public Health Laboratory and Department of Biological Sciences, University of Warwick, Coventry, UK

    J. Keith Struthers

Authors
  1. J. Keith Struthers
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Editor information

Editors and Affiliations

  1. Department of Medical Microbiology, Royal Free and University College Medical School, University College London, London, UK

    Stephen H. Gillespie

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© 2001 The Humana Press Inc., Totowa, NJ

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Struthers, J.K. (2001). The Use of a Continuous Culture System to Study the Antimicrobial Susceptibility of Bacteria in Biofilm. In: Gillespie, S.H. (eds) Antibiotic Resistence. Methods in Molecular Medicine™, vol 48. Humana Press. https://doi.org/10.1385/1-59259-077-2:215

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  • DOI: https://doi.org/10.1385/1-59259-077-2:215

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-777-9

  • Online ISBN: 978-1-59259-077-3

  • eBook Packages: Springer Protocols

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