Folate as a Targeting Device for Proteins Utilizing Folate Receptor-Mediated Endocytosis

Part of the Methods in Molecular Medicine™ book series (MIMM, volume 25)


Folic acid (M r = 441, Fig. 1 ) is a vitamin essential for de novo nucleotide synthesis and one-carbon metabolism. The ability to acquire folate, therefore, is important to the viability of proliferating cells.
Fig. 1.

Folic acid.


Folate Receptor Reduce Folate Carrier Protein Conjugate Desalting Column Free Folate 
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Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  1. 1.Endocyte, Inc.West Lafayette
  2. 2.Department of ChemistryPurdue UniversityWest Lafayette

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