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8 Determination of Plasma Homocysteine

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Atherosclerosis

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 52))

Introduction

A number of epidemiological and clinical studies have linked elevated plasma homocysteine (Hcy) to atherosclerotic vascular disease affecting coronary, carotid, and peripheral vessels. Plasma Hcy can be considered a marker of methionine metabolic efficiency, mainly affected by dietary intake of vitamins, especially folate, vitamin B6, and B12, as well as by genetic mutations of key metabolic enzymes and renal elimination.

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Authors and Affiliations

  1. Clinical Physiology Institute of CNR, Section of Milan, Department of Cardiology A. De Gasperis, Ospedale Niguarda Cà Granda, Milan, Italy

    Roberto Accinni & Oberdan Parodi

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  1. Roberto Accinni
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  2. Oberdan Parodi
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  1. Children’s Hospital Research Foundation, Cincinnati, OH

    Angela F. Drew

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Accinni, R., Parodi, O. (2001). 8 Determination of Plasma Homocysteine. In: Drew, A.F. (eds) Atherosclerosis. Methods in Molecular Medicine™, vol 52. Humana Press. https://doi.org/10.1385/1-59259-073-X:77

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  • DOI: https://doi.org/10.1385/1-59259-073-X:77

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-751-9

  • Online ISBN: 978-1-59259-073-5

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