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Localization of IL-4 and IL-5 mRNA in Bronchial Biopsies

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Asthma

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 44))

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Abstract

Cytokines are important biochemical mediators essential in initiating and maintaining inflammatory reactions associated with allergic disease in man. Although cytokines can be secreted from a variety of different cell types, considerable attention has been focused on T-lymphocyte-derived cytokines, which have been clearly implicated in the modulation of the immune system. Bronchial asthma is associated with persistent infiltration of the airways with activated CD4+T-lymphocytes, as well as other inflammatory cells exhibiting a T-helper type-2 (Th2)-like cytokine profile (13).

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© 2000 Humana Press Inc.

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Nakamura, Y., Christodoulopoulos, P., Hamid, Q. (2000). Localization of IL-4 and IL-5 mRNA in Bronchial Biopsies. In: Fan Chung, K., Adcock, I. (eds) Asthma. Methods in Molecular Medicine™, vol 44. Humana Press. https://doi.org/10.1385/1-59259-072-1:211

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  • DOI: https://doi.org/10.1385/1-59259-072-1:211

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-626-0

  • Online ISBN: 978-1-59259-072-8

  • eBook Packages: Springer Protocols

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