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Liquid Chromatographic Method for Aflatoxin M1 in Milk

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Mycotoxin Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 157))

Abstract

Aflatoxin M1 is the 4-hydroxy derivative of aflatoxin B1 (see Fig. 1). Aflatoxin M1 appears in milk and milk products as the direct result of the intake of aflatoxin B1 -contaminated feed by dairy cows (1). The amount excreted as aflatoxin M1, as a percentage of aflatoxin B1 in feed, is usually 1-4% (2), but values as high as 6% have been reported at μg daily intake levels of aflatoxin B1(3). The carry-over of aflatoxin B1 to milk may vary largely from animal to animal, from day to day, and from one milking to the next.

Chemical structure of aflatoxin M1.

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van Egmond, H.P., Dragacci, S. (2001). Liquid Chromatographic Method for Aflatoxin M1 in Milk. In: Trucksess, M.W., Pohland, A.E. (eds) Mycotoxin Protocols. Methods in Molecular Biology™, vol 157. Humana Press. https://doi.org/10.1385/1-59259-064-0:59

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  • DOI: https://doi.org/10.1385/1-59259-064-0:59

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-623-9

  • Online ISBN: 978-1-59259-064-3

  • eBook Packages: Springer Protocols

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