Reconstitution of Functional Integrin into Phopsholipid Vesicles and Planar Lipid Bilayers

  • Eva-Maria Erb
  • Jürgen Engel
Part of the Methods in Molecular Biology™ book series (MIMB, volume 139)

Abstract

Integrins are heterodimeric cell-surface receptors involved in a variety of functions such as binding to the ECM, regulation of the cellular organization, cell migration, proliferation, differentiation, and gene expression (1,2). Integrins in their native environment can diffuse in the plane of the membrane, and this mobility is required for processes like the assembly of integrins to focal contacts or cell migration (3,4).

Keywords

Vesicle Fusion Focal Contact Phospholipid Vesicle Total Internal Reflection Fluorescence Total Internal Reflection Fluorescence Microscopy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • Eva-Maria Erb
    • 1
  • Jürgen Engel
    • 1
  1. 1.Biocenter of the University of BaselBasel

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