Abstract
Neurotrophic factors play an essential role in the growth, survival, and differentiation of neurons in the nervous system. Several well-characterized neurotrophic factors, such as nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), NT-4/5, glial-cell-line-derived neurotrophic factor (GDNF), ciliary neurotrophic factor (CNTF), insulin-like growth factor-1 (IGF-I), are currently in clinical trials and have potential for the treatment of neurological diseases.
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© 2001 Humana Press Inc.
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Huang, BR., Ma, XM. (2001). Expression of Neurotrophic Factors such as GDNF in the E. coli System. In: Rush, R.A. (eds) Neurotrophin Protocols. Methods in Molecular Biology™, vol 169. Humana Press. https://doi.org/10.1385/1-59259-060-8:101
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DOI: https://doi.org/10.1385/1-59259-060-8:101
Publisher Name: Humana Press
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Online ISBN: 978-1-59259-060-5
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