Abstract
Monoclonal antibodies (MAbs) produced through the technique of somatic cell fusion are fundamental tools in the exploration of chemokine biology. This chapter details the procedures that were used to generate a panel of MAbs directed against the human chemokine RANTES (1,2). The general approach described here should be broadly applicable to the generation of MAbs directed against other members of this cytokine family.
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© 2000 Humana Press Inc.
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Nelson, P.J. (2000). 26The Production of Chemokine Specific Monoclonal Antibodies. In: Proudfoot, A.E.I., Wells, T.N.C., Power, C.A. (eds) Chemokine Protocols. Methods in Molecular Biology, vol 138. Humana Press. https://doi.org/10.1385/1-59259-058-6:223
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DOI: https://doi.org/10.1385/1-59259-058-6:223
Publisher Name: Humana Press
Print ISBN: 978-0-89603-722-9
Online ISBN: 978-1-59259-058-2
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