Abstract
Gap junction-mediated intercellular communications are known to be important for tissue growth, differentiation, and signaling (1). To experimentally probe the roles played by connexins in tissue development and function, we describe here a retroviral approach that has been successfully used to express nonviral exogenous connexins in embryonic chick lens in vivo (2). The expression of the retrovirally transduced connexin genes is found to be colocalized with their connexin counterparts in vivo.
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© 2001 Humana Press Inc.
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Jiang, J.X. (2001). Use of Retroviruses to Express Connexins. In: Bruzzone, R., Giaume, C. (eds) Connexin Methods and Protocols. Methods In Molecular Biology™, vol 154. Humana Press. https://doi.org/10.1385/1-59259-043-8:159
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DOI: https://doi.org/10.1385/1-59259-043-8:159
Publisher Name: Humana Press
Print ISBN: 978-0-89603-658-1
Online ISBN: 978-1-59259-043-8
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