Abstract
Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the mammalian nervous system and is an important mediator of numerous physiological effects (1). NPY elicits its manifold biological effects by interacting with at least six different G-protein-coupled receptors known as Y1, Y2, Y3, Y4, Y5, and y6 (2). The NPY Y1 and Y5 receptors have recently been the subject of intense basic research and drug development efforts because these two receptors appear to mediate the effects of NPY on food intake and the regulation of body weight. Unfortunately, the study of the NPY Y1 and Y5 receptors has been hampered by difficulties in expressing these two receptors in cultured cells.
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© 2000 Humana Press Inc.
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Parker, E.M. (2000). NeuropeptideYY5 Receptor Expression. In: Balasubramaniam, A. (eds) Neuropeptide Y Protocols. Methods in Molecular Biology™, vol 153. Humana Press. https://doi.org/10.1385/1-59259-042-X:53
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DOI: https://doi.org/10.1385/1-59259-042-X:53
Publisher Name: Humana Press
Print ISBN: 978-0-89603-662-8
Online ISBN: 978-1-59259-042-1
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