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Measurement of Macrophage-Mediated Cytolysis of Adenovirus-Infected Cells

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Adenovirus Methods and Protocols

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 21))

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Abstract

Macrophages are well-known for their ability to serve as phagocytes, ingesting and destroying microorganisms such as bacteria, and for their function in antigen presentation. Less appreciated, perhaps, is the fact that macrophages are also capable of recognizing and destroying certain abnormal self-cells; for example, some virus-infected and tumor cells are macrophage targets. This chapter describes an assay procedure by which the macrophagemediated cytolysis of such cells can be measured.

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References

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Author information

Authors and Affiliations

  1. Department of Biology, Georgia State University, Atlanta, GA

    Penelope J. Duerksen-Hughes

  2. Department of Microbilogy and Immunology, Emory University School of Medicine, Atlanta, GA

    Linda R. Gooding

Authors
  1. Penelope J. Duerksen-Hughes
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  2. Linda R. Gooding
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Editor information

Editors and Affiliations

  1. St. Louis University Health Science Center, St. Louis, MO

    William S. M. Wold

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© 1999 Humana Press Inc., Totowa, NJ

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Duerksen-Hughes, P.J., Gooding, L.R. (1999). Measurement of Macrophage-Mediated Cytolysis of Adenovirus-Infected Cells. In: Wold, W.S.M. (eds) Adenovirus Methods and Protocols. Methods in Molecular Medicine™, vol 21. Springer, Totowa, NJ. https://doi.org/10.1385/0-89603-551-4:113

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  • DOI: https://doi.org/10.1385/0-89603-551-4:113

  • Publisher Name: Springer, Totowa, NJ

  • Print ISBN: 978-0-89603-551-5

  • Online ISBN: 978-1-59259-603-4

  • eBook Packages: Springer Protocols

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