Molecular Evolutionary Analysis

Its Application in the Study of Hepatitis C Virus
  • Masashi Mizokami
  • Johnson Y. N. Lau
Part of the Methods in Molecular Medicine™ book series (MIMM, volume 19)

Abstract

The recent development of high-power personal computer hardware and software has allowed investigators to prepare phylogenetic trees without understanding of the fundamental principles of molecular evolution. Unfortunately, inexperienced investigators are also prone to draw inappropriate or wrong conclusions from this type of analysis. In particular, extreme caution should be taken when phylogenetic trees are applied to clinical settings.

Keywords

Adenine Pyrimidine Purine Cytosine Guanine 

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Copyright information

© Humana Press Inc., Totowa, NJ 1998

Authors and Affiliations

  • Masashi Mizokami
    • 1
  • Johnson Y. N. Lau
    • 2
  1. 1.Second Department of MedicineNagoya City University Medical SchoolNagoyaJapan
  2. 2.Research and DevelopmentICN PharmaceuticalsCosta Mesa

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