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Tissue Engineering Methods and Protocols pp 3–17Cite as

Preparation of Collagen—Glycosaminoglycan Copolymers for Tissue Regeneration

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Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 18))

Abstract

Certain analogs of the extracellular matrix (ECM) have been shown to possess surprising morphogenetic activity during healing of lesions in various anatomical sites. This chapter describes methods for synthesis of the two ECM analogs that have been studied most extensively. The reader is referred to descriptions of these methods in the original literature (1–3). The biological activity of ECM analogs has been reviewed elsewhere (4).

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Author information

Authors and Affiliations

  1. Fibers and Polymers Laboratory, Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA

    Lila J. Chamberlain & Ioannis V. Yannas

Authors
  1. Lila J. Chamberlain
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  2. Ioannis V. Yannas
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Editor information

Editors and Affiliations

  1. Center for Engineering in Medicine, Massachusetts General Hospital/Harvard Medical School, Boston, MA

    Jeffrey R. Morgan PhD  & Martin L. Yarmush MD  & 

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© 1999 Humana Press Inc., Totowa, NJ

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Chamberlain, L.J., Yannas, I.V. (1999). Preparation of Collagen—Glycosaminoglycan Copolymers for Tissue Regeneration. In: Morgan, J.R., Yarmush, M.L. (eds) Tissue Engineering Methods and Protocols. Methods in Molecular Medicine™, vol 18. Humana Press. https://doi.org/10.1385/0-89603-516-6:3

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  • DOI: https://doi.org/10.1385/0-89603-516-6:3

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-516-4

  • Online ISBN: 978-1-59259-602-7

  • eBook Packages: Springer Protocols

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