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Preclinical Behavioral Approaches to the Identification and Study of Antipsychotic Drug Action and Schizophrenia

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In Vivo Neuromethods

Part of the book series: Neuromethods ((NM,volume 32))

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Abstract

Schizophrenia is a group of illnesses of unknown origin with a yearly prevalence of 0.4–0.8% in the general population (Dohrenwend, 1980). Schizophrenia is characterized by a spectrum of symptoms that are commonly grouped into positive (including hallucinations, incoherence, delusions, distorted thought, and incongruity of affect) and negative (including poverty of speech, flat affect, low social drive, curbing of interest, and diminished sense of purpose) categories (Crow, 1980; Berrios, 1985; Kane, 1993a).

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Authors and Affiliations

  1. Clarke Institute of Psychiatry, Ontarto, Canada

    Sheena A. Josselyn & Franco J. Vaccarino

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  1. Sheena A. Josselyn
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  2. Franco J. Vaccarino
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© 1998 Humana Press Inc.

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Josselyn, S.A., Vaccarino, F.J. (1998). Preclinical Behavioral Approaches to the Identification and Study of Antipsychotic Drug Action and Schizophrenia. In: In Vivo Neuromethods. Neuromethods, vol 32. Humana Press. https://doi.org/10.1385/0-89603-511-5:177

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  • DOI: https://doi.org/10.1385/0-89603-511-5:177

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-511-9

  • Online ISBN: 978-1-59259-637-9

  • eBook Packages: Springer Protocols

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