Abstract
The ability of the polymerase chain reaction (PCR) to amplify from partially degraded and relatively impure preparations has allowed the technique to amplify nucleic acid sequences from archival materials, which in many institutions consist of paraffin-embedded tissue samples (1,2). This ability has allowed the carrying out of large scale retrospective studies of archival materials and has facilitated the use of materials from multiple institutions from different countries (3).
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© 1998 Humana Press Inc., Totowa, NJ
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Dennis Lo, Y.M. (1998). Amplification from Archival Materials. In: Lo, Y.M.D. (eds) Clinical Applications of PCR. Methods in Molecular Medicine™, vol 16. Humana Press. https://doi.org/10.1385/0-89603-499-2:21
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DOI: https://doi.org/10.1385/0-89603-499-2:21
Publisher Name: Humana Press
Print ISBN: 978-0-89603-499-0
Online ISBN: 978-1-59259-600-3
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