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Molecular Approaches for the Detection and Identification of β-Lactamases

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Molecular Bacteriology

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 15))

Abstract

β-lactamases confer resistance to β-lactam antibiotics, which are the most widely used family of antibiotics. It is, therefore, essential that one can identify the production of β-lactamases by clinical isolates and have effective ways of distinguishing the different enzymes. This is necessary for epidemiologic surveys, predicting future resistance trends, and to ensure that patients receive the appropriate β-lactam or alternative therapy.

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Author information

Authors and Affiliations

  1. Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, Collegeville, PA

    David J. Payne

  2. Department of Medical Microbiology, University of Edinburgh Medical School, Edinburgh, UK

    Christopher J. Thomson

Authors
  1. David J. Payne
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  2. Christopher J. Thomson
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Editors and Affiliations

  1. Central Public Health Laboratory, London, UK

    Neil Woodford  & Alan P. Johnson  & 

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© 1998 Humana Press Inc.

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Payne, D.J., Thomson, C.J. (1998). Molecular Approaches for the Detection and Identification of β-Lactamases. In: Woodford, N., Johnson, A.P. (eds) Molecular Bacteriology. Methods in Molecular Medicine™, vol 15. Humana Press. https://doi.org/10.1385/0-89603-498-4:495

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  • DOI: https://doi.org/10.1385/0-89603-498-4:495

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-498-3

  • Online ISBN: 978-1-59259-599-0

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