Abstract
The phosphoinositide cascade plays a central role in the transduction of many extracellular stimuli. Activation of plasma membrane-associated phosphoinositide-specific phospholipase C stimulates the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdInsP2) and generates inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), which in turn releases calcium from intracellular stores (1).
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Zhang, L. (1998). Inositol 1,4,5-Trisphosphate Mass Assay. In: Bird, I.M. (eds) Phospholipid Signaling Protocols. Methods in Molecular Biology™, vol 105. Humana Press. https://doi.org/10.1385/0-89603-491-7:77
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DOI: https://doi.org/10.1385/0-89603-491-7:77
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