G Proteins and Mood Disorders

  • Jun-Feng Wang
  • L. Trevor Young
Part of the Neuromethods book series (NM, volume 31)


A neurobiological basis for mood disorders has long been postulated, but is yet to be conclusively established. Earlier studies on the monoaminergic neurotransmitter systems in mood disorder have been very suggestive, although not conclusive, of alterations in these systems (noradrenergic, dopaminergic, serotonergic, and cholinergic) possibly owing to changes in receptor sensitivity (Post and Ballenger, 1984). These data have resulted in a recent and relatively extensive field of research investigating mechanisms that regulate receptor responsivity, which has focused to a large extent on the G protein-coupled signal transduction pathways.


Bipolar Disorder Major Depressive Disorder Mood Disorder Adenylyl Cyclase Antidepressant Drug 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Humana Press Inc 1997

Authors and Affiliations

  • Jun-Feng Wang
    • 1
  • L. Trevor Young
    • 1
  1. 1.Department of Psychiatry and Biomedical SciencesMcMaster UniversityHamiltonCanada

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