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Biomolecular Interaction Analysis

Strategies for Antibody and Antigen Characterization

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Molecular Diagnosis of Infectious Diseases

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 13))

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Abstract

One of the most important classes of reagents for clinical diagnosis is antibodies, either in polyclonal preparations, as monoclonal antibodies (MAbs), or as customized reagents prepared by genetic engineering. The enormous range of antibodies produced by hybridoma and recombinant technologies, together with the requirements of clinical diagnosis for sensitivity and selectivity, make heavy demands on the processes of selecting and characterizing suitable antibody reagents.

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Author information

Authors and Affiliations

  1. Biacore, Pharmacia, Freiberg, Germany

    Uwe W. Roder

  2. Biacore, Uppsala, Sweden

    Francis Markey

Authors
  1. Uwe W. Roder
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  2. Francis Markey
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Editor information

Editors and Affiliations

  1. University of Regensburg, Germany

    Udo Reischl

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© 1998 Humana Press Inc.

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Roder, U.W., Markey, F. (1998). Biomolecular Interaction Analysis. In: Reischl, U. (eds) Molecular Diagnosis of Infectious Diseases. Methods in Molecular Medicine™, vol 13. Humana Press, Totowa, NJ. https://doi.org/10.1385/0-89603-485-2:531

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  • DOI: https://doi.org/10.1385/0-89603-485-2:531

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-0-89603-485-3

  • Online ISBN: 978-1-59259-597-6

  • eBook Packages: Springer Protocols

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