Abstract
In many ways, the liver represents an ideal target organ for gene delivery. Anatomically, the sheer bulk cof its tissue mass and its dual blood supply are advantageous for intravascular injection of virus into either portal or systemic circulation. The portal vein provides a direct iv route into the liver. It also theoretically provides an indirect route by oral administration since the portal system drains the gut.
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© 1997 Humana Press Inc., Totowa, NJ
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Barr, D., Kay, M.A. (1997). Methods for Delivery of Genes to Hepatocytes In Vivo Using Recombinant Adenovirus Vectors. In: Robbins, P.D. (eds) Gene Therapy Protocols. Methods in Molecular Medicine, vol 7. Humana, Totowa, NJ. https://doi.org/10.1385/0-89603-484-4:205
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DOI: https://doi.org/10.1385/0-89603-484-4:205
Publisher Name: Humana, Totowa, NJ
Print ISBN: 978-0-89603-484-6
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