Abstract
Poxviruses are large, double-stranded DNA viruses that replicate in the cytoplasm of infected cells. The family Poxviridae is divided into two subfamilies, the Entomopoxvirinae of insects and the Chordopoxvirinae of vertebrates; the latter consists of eight genera and several unclassified viruses, The genus Orthopoxvirus comprises morphologically and antigenically closely related viruses, including the now eradicated variola (smallpox) virus and several pathogens of veterinary and zoonotic importance.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Esposito, J. J., Baxby, D., Black, D. N., Dales, S., Darai, G., Dumbell, K R, Granados, R R., Joklik, W. K., McFadden, G., Moss, B., Moyer, R. W., Pickup, D. J., Robinson, A. J., Tripathy, D. N. (1995) Poxviridae, in Virus Taxonomy Classification and Nomenclature of viruses Sixth Report of the International Commitiee on Taxonomy of Viruses (Murphy, F. A., Fauquet, C. M, Bishop, D. H. L, Gabrial, S. A, Jarvis, A W., Martelli, G P., Mayo, M A., and Summers, M. D., (eds.), Arch Virol Suppl.10, 79ā91.
Fenner, F., Wittek, R., and Dumbell, K. R. (1989) The Orthopoxviruses, Academic Press, New York.
Mackett, M. and Archard, L C. (1979) Conservation and variation in orthopoxvirus genome structure. J. Gen. Virol 45, 683ā701.
Esposito, J. J. and Knight, J. C. (1985) Orthopoxvirus DNA. comparison of restriction profiles and maps. Virology 143, 230ā251.
Meyer, H., Pfeffer, M., and Rziha, H.-J. (1994) Sequence alterations within and downstream of the A-type inclusion protein genes allow differentiation of Orthopoxvirus species by polymerase chain reaction. J Gen. Virol 75, 1975ā1981.
Ropp, S L., Jin, Q., Knight, J. C., Massung, R. F., and Esposito, J J (1995) Polymerase cham reaction strategy for identification and differentiation of smallpox and other orthopoxviruses. J Clin. Microbiol 33, 2069ā2076
Knight, J. C., Massung, R. F., and Esposito, J. J. (1995) Polymerase chain reaction identification of smallpox virus, in Diagnosis of Human Viruses by Polymerase Chain Reaction Technology, 2nd ed (Becker, Y. and Darai, G, eds), Springer-Verlag, Berlin, pp 297ā302
Esposito, J, J and Massung, R F. (1995) Poxvirus infections in humans, in Manual of Clinical Microbiology, 6th ed. (Murray, P R., Tenover, F., Baron, E. J., Pfaller, M. A., and Yolken, R. H, eds.), American Society for Microbiology, Washington, DC, pp 1131ā1138.
Esposito, J. J. and Nakano, J. H. (1988) Poxviridae the poxviruses in laboratory diagnosis of infectious diseases, in Viral, Rickettsial and Chlamydial Diseases, vol. 2 (Lennette, E, H, Halonen, P, and Murphy, F A, eds.), SpringerVerlag, New York, pp. 177ā207
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
Ā© 1998 Humana Press Inc.
About this protocol
Cite this protocol
Meyer, H., Ropp, S.L., Esposito, J.J. (1998). Poxviruses. In: Stephenson, J.R., Warnes, A. (eds) Diagnostic Virology Protocols. Methods in Molecular Medicineā¢, vol 12. Springer, Totowa, NJ. https://doi.org/10.1385/0-89603-479-8:199
Download citation
DOI: https://doi.org/10.1385/0-89603-479-8:199
Publisher Name: Springer, Totowa, NJ
Print ISBN: 978-0-89603-479-2
Online ISBN: 978-1-59259-596-9
eBook Packages: Springer Protocols