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A PCR-Based Approach to Hammerhead Ribozyme Synthesis

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Book cover Therapeutic Applications of Ribozymes

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 11))

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Abstract

Inactivation of gene expression by antisense mechanisms in general and by ribozymes in particular show great promise as a research tool as well as therapeutic agent in selectively reducing mRNA species and thus decreasing subsequent protein synthesis (for reviews see refs. 1 and 2).

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Author information

Authors and Affiliations

  1. Neurosurgery and Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, PA

    Katalin Karikó

  2. Cardiovascular Division, University of Pennsylvania, Philadelphia, PA

    Elliot S. Barnathan

Authors
  1. Katalin Karikó
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  2. Elliot S. Barnathan
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Editor information

Editors and Affiliations

  1. Berlex Biosciences, Richmond, CA

    Kevin J. Scanlon

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© 1998 Humana Press Inc.

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Karikó, K., Barnathan, E.S. (1998). A PCR-Based Approach to Hammerhead Ribozyme Synthesis. In: Scanlon, K.J. (eds) Therapeutic Applications of Ribozymes. Methods in Molecular Medicine™, vol 11. Springer, Totowa, NJ. https://doi.org/10.1385/0-89603-477-1:427

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  • DOI: https://doi.org/10.1385/0-89603-477-1:427

  • Publisher Name: Springer, Totowa, NJ

  • Print ISBN: 978-0-89603-477-8

  • Online ISBN: 978-1-59259-595-2

  • eBook Packages: Springer Protocols

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