Abstract
A biochemical paradox that has been observed for many years is now becoming understood: O2, essential for the aerobic life forms, can be inappropriately metabolized, becoming toxic to an organism. Mammals derive most of their cellular adenosine triphosphate (ATP) from the controlled four-electron reduction of O2, to form H2O by the mitochondrial electron-transport system. Approximately 98% of all O2 consumed by cells enters the mitochondria, where it is reduced by a terminal oxidase, such as cytochrome oxidase.
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© 1998 Humana Press Inc., Totowa, NJ
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Stadler, I. (1998). Oxygen Consumption Methods. In: Armstrong, D. (eds) Free Radical and Antioxidant Protocols. Methods in Molecular Biology™, vol 108. Humana Press. https://doi.org/10.1385/0-89603-472-0:3
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DOI: https://doi.org/10.1385/0-89603-472-0:3
Publisher Name: Humana Press
Print ISBN: 978-0-89603-472-3
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