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EPR Measurements of Nitric Oxide-Induced Chromanoxyl Radicals of Vitamin E

Interactions with Vitamin C

  • Protocol
Free Radical and Antioxidant Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 108))

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Abstract

Tocopherols (vitamin E) are the major lipid-soluble chain-breaking antioxidants of membranes and blood plasma (1–3). Antioxidant function of tocopherols is confined to their chromanol nucleus with 6-hydroxy group, and is based on the ability of the latter to reduce different radicals (e.g., lipid peroxyl radicals [LOO*], oxygen radicals) yielding chromanoxyl radicals (2–4).

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Author information

Authors and Affiliations

  1. Department of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA

    Valerian E. Kagan

  2. Department of Respiratory Research, Walter Reed Army Institute of Research, Washington, DC

    Nikolai V. Gorbunov

Authors
  1. Valerian E. Kagan
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  2. Nikolai V. Gorbunov
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Editor information

Editors and Affiliations

  1. State University of New York, Buffalo, NY

    Donald Armstrong

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© 1998 Humana Press Inc., Totowa, NJ

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Kagan, V.E., Gorbunov, N.V. (1998). EPR Measurements of Nitric Oxide-Induced Chromanoxyl Radicals of Vitamin E. In: Armstrong, D. (eds) Free Radical and Antioxidant Protocols. Methods in Molecular Biology™, vol 108. Humana Press. https://doi.org/10.1385/0-89603-472-0:277

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  • DOI: https://doi.org/10.1385/0-89603-472-0:277

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-472-3

  • Online ISBN: 978-1-59259-254-8

  • eBook Packages: Springer Protocols

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