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Apoptosis Techniques and Protocols pp 99–132Cite as

Apoptosis and Ischemia in the Central Nervous System

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Part of the book series: Neuromethods ((NM,volume 29))

Abstract

Our understanding of apoptosis and programmed cell death has rapidly evolved over the last decade. As originally conceived, apoptosis was a purely morphological phenomena based on the appearance of membrane blebbing (apoptotic bodies) and nuclear changes, including chromatin condensation and DNA fragmentation. Likewise, programmed cell death was a developmental definition describing the physiologically appropriate “programmed” death of cells during developmental modeling and morphogenesis.

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Authors
  1. Matthew D. Linnik
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  1. Douglas Hospital Research Centre, Verdun, Canada

    Judes Poirier

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Linnik, M.D. (1997). Apoptosis and Ischemia in the Central Nervous System. In: Poirier, J. (eds) Apoptosis Techniques and Protocols. Neuromethods, vol 29. Humana Press. https://doi.org/10.1385/0-89603-451-8:99

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  • DOI: https://doi.org/10.1385/0-89603-451-8:99

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-451-8

  • Online ISBN: 978-1-59259-634-8

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