Abstract
The four general methods to generate and screen a huge combinatorial peptide library (>107 peptides) are: biological libraries such as filamentous phage (1), plasmid (2), or polysome (3) libraries; the “one-bead one-compound” synthetic combinatonal library method or the “Selectlde process” (4–6); synthetic peptide library methods that require deconvolution, such as an iterative approach (7,8), positional scanning (9); orthogonal partition approach (10), or recurse deconvolution (11); and synthetic library using affinity column selection method (12,13).
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© 1998 Humana Press Inc., Totowa, NJ
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Lam, K.S., Lebl, M. (1998). Synthesis of a One-Bead One-Compound Combinatorial Peptide Library. In: Cabilly, S. (eds) Combinatorial Peptide Library Protocols. Methods in Molecular Biology™, vol 87. Humana Press. https://doi.org/10.1385/0-89603-392-9:1
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DOI: https://doi.org/10.1385/0-89603-392-9:1
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