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Cancer Vaccines

  • Lindy G. Durrant
  • T. J. Declan Buckley
Part of the Methods in Molecular Medicine™ book series (MIMM, volume 4)

Abstract

In the past there was considerable evidence that cellular rather than antibody responses were more effective for tumor rejection (1). However, the task of identifying the tumor antigens recognized by T-cells was daunting technically. More recently there has been a growing optimism that the potential of tumor immunotherapy may at last be realized. This enthusiasm has been fed by a better understanding of the presentation and processing of peptides necessary for the induction of immune responses and the identification of new tumor targets. These developments will be discussed in this chapter. Because cancer vaccines are still in their infancy and largely experimental, detailed protocols for their production will not be presented.

Keywords

Major Histocompatibility Complex Major Histocompatibility Complex Class Tumor Antigen Major Histocompatibility Complex Molecule Major Histocompatibility Complex Binding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Humana Press Inc, Totowa, NJ 1996

Authors and Affiliations

  • Lindy G. Durrant
    • 1
  • T. J. Declan Buckley
    • 1
  1. 1.Department of Clinical OncologyCity HospitalNottinghamUK

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