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Protein NMR Techniques pp 271–297Cite as

NMR Studies of Peptides and Proteins Associated with Membranes

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Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 60))

Abstract

High-resolution structural information about peptides and proteins associated with membranes now can be obtained from experimental studies involving both multidimensional solution and high resolution solid-state NMR spectroscopy. The relatively recent development and application of NMR spectroscopy for studies of membrane proteins takes advantage of the two well-characterized model membrane environments of detergent micelles and phospholipid bilayers (Fig. 1).

Representation of model membranes. (A) Micelle, (B) bilayer.

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  1. Department of Chemistry, University of Pennsylvania, Philadelphia, PA

    R. Bryan Klassen & Stanley J. Opella

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  1. R. Bryan Klassen
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  2. Stanley J. Opella
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  1. SmithKline Beecham Pharmaceuticals, Welwyn, Hertfordshire, UK

    David G. Reid

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© 1997 Humana Press Inc.

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Klassen, R.B., Opella, S.J. (1997). NMR Studies of Peptides and Proteins Associated with Membranes. In: Reid, D.G. (eds) Protein NMR Techniques. Methods in Molecular Biology™, vol 60. Humana Press. https://doi.org/10.1385/0-89603-309-0:271

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  • DOI: https://doi.org/10.1385/0-89603-309-0:271

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-309-2

  • Online ISBN: 978-1-59259-546-4

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