Abstract
The potential irritancy of compounds may be detected by observing adverse changes that occur in the chorionallantoic membrane of the egg after exposure to test chemicals (1).
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References
Lupke, N. P. (1986) (hen’s egg test) in toxicological research, in Skin Models. Models to Study Function and Disease of Skin (Marks, R. and Plewig, G., eds.), Springer-Verlag, pp. 282–291.
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Spielmann, H., Gerner, I., Kalweit, S., Moog, R., Wirnsberger, T, Krauser, K, et al. (1991) Interlaboratory assessment of alternatives to the Draize eye irritation test in Germany. Toxic In Vitro 5, 539–542
Spielmann, H., Kalwert, S, Liebsch, M., Wirnsberger, T, Gerner, I., Bertram-Neis, E., et al. (1993) Validation study of alternatives to the Draize eye irritation test in Germany: cytotoxicity testing and HET-CAM test with 136 industrial chemicals. Toxicol. In Vitro 7, 505–510.
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© 1995 Humana Press Inc , Totowa, NJ
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Spielmann, H. (1995). HET-CAM Test. In: O’Hare, S., Atterwill, C.K. (eds) In Vitro Toxicity Testing Protocols. Methods in Molecular Biology™, vol 43. Humana Press. https://doi.org/10.1385/0-89603-282-5:199
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DOI: https://doi.org/10.1385/0-89603-282-5:199
Publisher Name: Humana Press
Print ISBN: 978-0-89603-282-8
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