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Alternative Method of Assessing Toxicity

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In Vitro Toxicity Testing Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 43))

Abstract

The safety assessment of new chemicals and pharmaceuticals and the incorporation of these data into a human risk assessment package requires a large number of expensive, regulated tests in animal species including, in some cases, nonhuman primates (1–3).

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References

  1. Volans, G. N., Sims, J., Sullivan, F. M., and Turner, P. (eds.) (1989) Basic Science in Toxicology, V International Congress of Toxicology (ICTV), Taylor & Francis.

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  2. Poole, A. and Leslie, G. B, eds. (1989) A Practical Approach to Toxological Investigations, Cambridge University Press.

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  3. Lumley, C., Parkmson, C, and Walker, S. R. (1992) An international appraisal of the minimum duration of chronic animal toxicity studies. Hum. Exp. Toxicol. 11, 155–162

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  4. Parish, W. E. and Hard, G. C. (eds.), Toxicology In Vitro. Proceedings of Second International Conference on Practical In Vitro Toxicology 4/5.

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  5. Atterwill, C. K. and Steele, C. E., eds. (1987) In-Vitro Methods in Toxicology, Cambridge University Press, Cambridge.

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  6. Walum, E., Stenberg, K., and Jenssen, D. (1990) Understanding Cell Toxicology—Principles and Practice, Ellis Horwood, New York, London, Sydney.

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  7. OECD Environment Monograph No. 36. Scientific Criteria for Validation of In Vitro Toxicity Tests, Sept. 1990.

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  8. FRAME 21st Anniversary Issue (1990) ATLA, 18.

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Author information

Authors and Affiliations

  1. University of Hertfordshire, Hatfield, UK

    Chris K. Atterwill

Authors
  1. Chris K. Atterwill
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Editor information

Editors and Affiliations

  1. University of Hertfordshire, Hatfield, UK

    Sheila O’Hare  & Chris K. Atterwill  & 

Copyright information

© 1995 Humana Press Inc , Totowa, NJ

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Cite this protocol

Atterwill, C.K. (1995). Alternative Method of Assessing Toxicity. In: O’Hare, S., Atterwill, C.K. (eds) In Vitro Toxicity Testing Protocols. Methods in Molecular Biology™, vol 43. Humana Press. https://doi.org/10.1385/0-89603-282-5:1

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  • DOI: https://doi.org/10.1385/0-89603-282-5:1

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-282-8

  • Online ISBN: 978-1-59259-530-3

  • eBook Packages: Springer Protocols

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